Donald E Wesson Selected Research

Acidosis

1/2022	Effects of veverimer on serum bicarbonate and physical function in women with chronic kidney disease and metabolic acidosis: a subgroup analysis from a randomised, controlled trial.
1/2022	Effects of veverimer on serum bicarbonate and physical function in diabetic patients with chronic kidney disease and metabolic acidosis: subgroup analysis from a randomized, controlled trial.
1/2021	The Continuum of Acid Stress.
1/2021	Treatment of Chronic Kidney Disease-Related Metabolic Acidosis With Fruits and Vegetables Compared to NaHCO3 Yields More and Better Overall Health Outcomes and at Comparable Five-Year Cost.
1/2020	Mechanisms of Metabolic Acidosis-Induced Kidney Injury in Chronic Kidney Disease.
4/2019	Veverimer versus placebo in patients with metabolic acidosis associated with chronic kidney disease: a multicentre, randomised, double-blind, controlled, phase 3 trial.
1/2019	Urine citrate excretion identifies changes in acid retention as eGFR declines in patients with chronic kidney disease.
1/2019	Long-term safety and efficacy of veverimer in patients with metabolic acidosis in chronic kidney disease: a multicentre, randomised, blinded, placebo-controlled, 40-week extension.
1/2019	Metabolic Acidosis 1 Year Following Kidney Transplantation and Subsequent Cardiovascular Events and Mortality: An Observational Cohort Study.
1/2019	Fruit and Vegetable Treatment of Chronic Kidney Disease-Related Metabolic Acidosis Reduces Cardiovascular Risk Better than Sodium Bicarbonate.

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Donald E Wesson Research Topics

Disease

24	Acidosis 01/2022 - 04/2010
23	Chronic Renal Insufficiency 01/2022 - 03/2006
6	Chronic Kidney Failure (Chronic Renal Failure) 03/2020 - 11/2006
5	Kidney Diseases (Kidney Disease) 01/2022 - 11/2012
4	Hypertension (High Blood Pressure) 01/2019 - 03/2006
4	Albuminuria 08/2014 - 01/2003
4	Hypertensive Nephropathy 03/2013 - 04/2010
3	Cardiovascular Diseases (Cardiovascular Disease) 03/2020 - 03/2006
3	Essential Hypertension 01/2017 - 09/2005
2	Inflammation (Inflammations) 01/2020 - 03/2014
2	Disease Progression 01/2020 - 04/2019
2	Fibrosis (Cirrhosis) 01/2020 - 03/2014
2	Cysts 01/2017 - 01/2016
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2017 - 01/2016
2	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2017 - 01/2016
2	Renal Insufficiency (Renal Failure) 11/2015 - 12/2010
2	Type 2 Diabetes Mellitus (MODY) 02/2004 - 01/2003
1	Hyperkalemia 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Uremia 01/2020
1	Bone Resorption 04/2019
1	Nausea 04/2019
1	Constipation 04/2019
1	Flatulence 04/2019
1	Frailty 01/2019
1	Sickle Cell Anemia (Hemoglobin S Disease) 08/2014
1	Vascular Diseases (Vascular Disease) 08/2014
1	Anemia 08/2014
1	Hypoxia (Hypoxemia) 02/2012
1	Hyperoxia 01/2004
1	Ischemia 01/2004
1	Diabetic Nephropathies (Diabetic Nephropathy) 02/2002

Drug/Important Bio-Agent (IBA)

32	AcidsIBA 01/2021 - 05/2009
12	Bicarbonates (Hydrogen Carbonate)IBA 01/2022 - 08/2010
11	AlkaliesIBA 01/2021 - 12/2010
7	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 04/2019 - 08/2010
7	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2017 - 02/2002
6	Proteins (Proteins, Gene)FDA Link 01/2019 - 11/2012
4	veverimerIBA 01/2022 - 01/2019
4	Angiotensin IIIBA 01/2020 - 12/2012
4	AldosteroneIBA 01/2020 - 12/2010
4	CreatinineIBA 01/2019 - 01/2003
4	AlbuminsIBA 01/2019 - 01/2003
4	Endothelins (Endothelin)IBA 03/2014 - 04/2010
3	Hydrochloric Acid (Hydrogen Chloride)FDA Link 01/2022 - 04/2019
3	Citric Acid (Citrate)FDA LinkGeneric 01/2019 - 09/2012
2	Muscle Proteins (Muscle Protein)IBA 01/2022 - 01/2022
2	PolymersIBA 01/2022 - 01/2022
2	SodiumIBA 01/2019 - 01/2017
2	dioxotechnetiumIBA 01/2019 - 11/2014
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2003 - 02/2002
1	sodium zirconium cyclosilicateIBA 01/2021
1	Endothelin-1 (Endothelin 1)IBA 01/2020
1	AmmoniaIBA 01/2020
1	Hormones (Hormone)IBA 01/2020
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2020
1	Pharmaceutical PreparationsIBA 04/2019
1	Serum AlbuminIBA 01/2019
1	SuspensionsIBA 01/2019
1	Dietary SodiumIBA 01/2017
1	Urea (Carbamide)FDA LinkGeneric 01/2017
1	SaltsIBA 01/2016
1	LipidsIBA 11/2015
1	AngiotensinogenIBA 11/2014
1	Oxygen (Dioxygen)IBA 08/2014
1	Erythropoietin FDA Link 02/2012
1	Transforming Growth Factor beta (TGF-beta)IBA 02/2012
1	NF-kappa B (NF-kB)IBA 02/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2012
1	Dietary ProteinsIBA 01/2012
1	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 04/2011
1	Mineralocorticoid Receptor AntagonistsIBA 12/2010
1	Sodium Chloride FDA LinkGeneric 08/2010
1	Antihypertensive Agents (Antihypertensives)IBA 08/2010
1	8-epi-prostaglandin F2alphaIBA 11/2006
1	ProstaglandinsIBA 11/2006
1	Hemoglobins (Hemoglobin)IBA 11/2006
1	IsoprostanesIBA 11/2006
1	Scavenger Receptors (Scavenger Receptor)IBA 11/2006
1	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2004
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2004

Therapy/Procedure

7	Therapeutics 04/2019 - 02/2004
5	Nephrectomy 01/2019 - 12/2010
1	Renal Replacement Therapy (Therapies, Renal Replacement) 03/2020
1	Kidney Transplantation 01/2019